DOSE:

75 mg

insufflated

Ketamine

(powder / crystals)

BODY WEIGHT:

145 lb

A month ago while showing my mom how a bug bite had progressed she discovered that it looked awfully like the bite that a doctor said was "probably lyme" not too long ago. She has chronic lyme which has been improved by various obscure treatments and had recently restarted bee venom therapy in response to her own bite. Because we had the bees on hand, we started my course of bee venom therapy for my own infection. There is no clinical research of the therapy in human bodies but based off of anecdotal evidence and petri dish research it seems to kill off the offending bacteria. It is usually done in cases of chronic lyme but we chose to use it in our acute cases after my mom had a horrible response to doxycycline. In short, the bee venom therapy process starts with 1 sting 3 times a week (for me it is Monday, Wednesday, and Friday) and ramps up to 10. At the time of the experience I was on 3 stings.

We both enjoy exploring altered spaces and we share our liking for ketamine in particular. I had last done ketamine about a month prior, a couple days before we noticed my bite developing a red ring. Her last dose was likely months before that and she does not use often enough for me to expect for her to have any significant permatolerance.

This week we discussed if it would be safe or not to do and we decided that the only risk would be trouble processing both the bee venom and the ketamine, which likely wouldn't pose any long term risk from one dose. On Thursday after having to skip her sting on Wednesday she went into a ketamine experience which she said was underwhelming. I had directed her to do only 50mg and I was wondering if it just wasn't the dose she wanted. After having now done it myself in similar conjunction to stings (last sting was on Friday, next sting on Monday, did my ketamine on Sunday night) it seems as if the bee venom conditions the body to rapidly discard the ketamine.

I am running short on ketamine so I went through all of my tin foils that are likely a year old. I surprisingly found an extra 25mg through this method. I weighed out another 50mg from my more recent ketamine purchase to make about 75mg. For me this is the highest dose that I would consider in the psycholytic range. I don't go off into too far of a dissociated ego state, but it gives me great perspective.

I readied three lines, doing my third about 5 minutes out from my initial insufflation into the nostril which I find most receptive. I was launched into an altered headspace immediately upon dosing, possibly a euphoria stemming from my joy of insufflation and completely unrelated to the substance. After doing my third line I spent a couple minutes on my guitar as I was intensely inspired to learn the intro to the first song on the playlist I had prepared, but quickly retired this idea and settled down.

My playlist started with "plowing into the field of love" by iceage and then descended into ambient. I laid down on my bed with my eyes closed and began drifting off in the ways I expected to. I remember eventually recognizing the come up as not being as intense as I expected, but reminding myself that I was still within the first 20 minutes. Music was both flattened and immersive which is the way I usually experience music on ketamine. I had a bit of a buzzing sensation in my arms and I felt physically altered by all of the different tones within my music.

I realized that I'd really enjoy moving my box fan on to my bedside table so it would blow on me. My motor skills were altered but still pretty intact and I had no issues with this task. Once I got everything set up, which probably took less than 3 minutes, I laid back down and found a creeping disappointment. It seemed as if my whole experience had stopped.

I meditated for a few minutes, thinking maybe I needed to relax back into the headspace after interrupting it, but found nothing. I picked up my phone and complained to my friend, wondering if trying to do normal activities would reveal how altered I really was. About 40 minutes after dosing, I was almost entirely back to baseline, something I would not expect with 75mg. My motor skills were slightly altered, but hardly anything noticeable.

Because my mom had a similar experience the default assumption is that it has something to do with the bee venom therapy. There are still other factors at play, but I wouldn't expect any of them to produce this experience. One factor is that 25mg of my dose was old product, but I wouldn't expect a 50mg experience to be this light and brief either. It was also around 10pm when I dosed and when I laid back down after setting up my fan I felt more sleepy than altered. Perhaps sleepiness overrode my experience?

This is of course a single trial so I cannot feel confident in any explanation. While I would love to experiment further, my ketamine source has almost doubled their price from what I originally was purchasing at. I probably have about 200mg left and while my mom possesses a stockpile, I feel no interest in attempting a further ketamine experience at this time.

Bee venom is purported to have serotonergic properties, so it is advised to avoid serotonergic drugs. Although the risk of serotonin syndrome is likely quite low, I am not a person who takes risks that impact my long term health at any considerable risk level. I was hoping that ketamine could be my saving grace giving me access to a psychedelic headspace in the coming months while I continue my therapy, but it seems as I will have to stick with cannabis as my only mind altering tool for this journey.

Exp Year: 2025	ExpID: 119220
Gender: Not Specified
Age at time of experience: 20
Published: Sep 11, 2025	Views: Not Supported
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Ketamine (31) : Combinations (3), Preparation / Recipes (30), General (1), Alone (16)